Nicholas Taylor

Current Project

Cryo-EM of Membrane Proteins

Short Biography

Nicholas Taylor from Belgium joined the Stahlberg group at C-CINA in July 2016. Previously he has been a postdoc at EPFL (Lausanne, Switzerland) and CIB-CSIC (Madrid, Spain). He obtained his PhD in Molecular Biology at EMBL Heidelberg (Germany). Before that, he performed his master thesis research at UCL (London, UK). He has a master degree in Biochemistry from Ghent University (Belgium) and a “candidate” degree in Biomedical Sciences from Free University Brussels (VUB) (Belgium).

Publications

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Cryo-EM structure of the rhodopsin-G-alpha-i-beta-gamma complex reveals binding of the rhodopsin C-terminal tail to the G-beta subunit

Tsai, C.J., Marino, J., Adaixo, R., Pamula, F., Muehle, J., Maeda, S., Flock, T., Taylor, N., Mohammed, I., Matile, H., Dawson, R.J.P., Deupi, X., Stahlberg, H., Schertler, G.F.X.

(submitted), (2019)

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Cryo-EM structures of a human ABCG2 mutant trapped in ATP-bound and substrate-bound states

Manolaridis, I., Jackson, S.M., Taylor, N., Kowal, J., Stahlberg, H., Locher, K.

Nature 563(7731), 426-430 (2018)

PubMed

DOI: DOI

5

Cryo-EM structure of alpha-synuclein fibrils

Guerrero-Ferreira, R., Taylor, N., Mona, D., Ringler, P., Lauer, M.E., Riek, R., Britschgi, M., Stahlberg, H.

eLife 7(e36402), (2018)

PubMed

DOI: DOI

4

Structural basis of small-molecule inhibition of human multidrug transporter ABCG2

Jackson, S.M., Manolaridis, I., Kowal, J., Zechner, M., Taylor, N., Bause, M., Bauer, S., Bartholomaeus, R., Bernhardt, G., Koenig, B., Buschauer, A., Stahlberg, H., Altmann, K.H., Locher, K.P.

Nature Struct. Mol. Biol. 25(4), 333-340 (2018)

PubMed

DOI: DOI

3

Structure of the human multidrug transporter ABCG2

Taylor, N., Manolaridis, I., Jackson, S.M., Kowal, J., Stahlberg, H., Locher, K.P.

Nature 546, 504-509 (2017)

PubMed

DOI: doi

2

Atomic structure of bacteriophage T4 baseplate and its function in triggering sheath contraction

Taylor, N., Prokhorov, N.S., Guerrero-Ferreira, R.C., Shneider, M.M., Browning, C., Goldie, K., Stahlberg, H., Leiman, P.G.

Nature 533(7603), 346-352 (2016)

PubMed

DOI: 10.1038/nature17971

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