Ricardo Adaixo

Current Project

Study of membrane protein structure and function by electron microscopy with a particular focus on human proteins and protein-lipid interactions

Short Biography

Ricardo Adaixo from Portugal joined the Stahlberg group as a PhD candidate in October 2015. He completed his Masters in Biochemistry at Faculdade de Ciências, University of Porto, focusing on potassium channels by X-ray crystallography. His current scientific interests include Membrane Proteins, Cryo-EM, Single Particle Analysis and Protein Expression and Purification.

Publications

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Functional and structural characterization of Serratia marcescens ExbB: determinants of the interaction with HasB/TonB

Biou, V., Adaixo, R., Chami, M., Coureux. P., Laurent B., Ntsogo, Y., Cardoso de Amorim, G., Izadi-Pruneyre, N., Malosse, C., Chamot-Rooke, J., Stahlberg, H., Delepelaire, P.

bioRxiv.org 2021.04.21.440815, (2021)

DOI: bioRxiv

5

Cryo-EM structural studies of the agonist complexed human TRPV4 ion-channel reveals novel structural rearrangements resulting in an open-conformation

Botte, M., Ulrich, A.K.C., Adaixo, R., Gnutt, D., Brockmann, A., Bucher, D., Chami, M., Bocquet, N., Ebbinghaus-Kintscher, U., Puetter, V., Becker, A., Egner, U., Stahlberg, H., Hennig, M., Holton, S.J.

bioRxiv , 2020.10.13.334797 (2020)

DOI: DOI

4

Cryo-EM structure of the rhodopsin-G-alpha-i-beta-gamma complex reveals binding of the rhodopsin C-terminal tail to the G-beta subunit

Tsai, C.J., Marino, J., Adaixo, R., Pamula, F., Muehle, J., Maeda, S., Flock, T., Taylor, N., , ., Matile, H., Dawson, R.J.P., Deupi, X., Stahlberg, H., Schertler, G.F.X.

eLife 8;e46041, (2019)

PubMed

DOI: DOI

3

An iris diaphragm mechanism to gate a cyclic nucleotide-gated ion channel

Marchesi, A., Gao, X., Adaixo, R., Rheinberger, J., Stahlberg, H., Nimigean, C., Scheuring, S.

Nature Comm. 9(1), 3978 (2018)

PubMed

DOI: DOI

2

Blotting-free and lossless cryo-electron microscopy grid preparation from nanoliter-sized protein samples and single-cell extracts

Arnold, S., Albiez, S., Bieri, A., Syntychaki, A., Adaixo, R., McLeod, R., Goldie, K., Stahlberg, H., Braun, T.

J. Struct. Biol. (197), 220-226 (2017)

PubMed

DOI: 10.1016/j.jsb.2016.11.002

1

2015-2021, PhD Student, PostDoc

+41 61 387 32 25

C-CINA, Biozentrum, Uni Basel, Mattenstrasse 26, Room P12, CH-4058 Basel, Switzerland

ricardo.adaixo@unibas.ch